INTRATUMORAL MICROBIOME: FOE OR FRIEND IN RESHAPING THE TUMOR MICROENVIRONMENT LANDSCAPE?


Genetic analysis of a major international collection of cultivated apple varieties reveals previously unknown historic heteroploid and inbred relationships.

Domesticated apple (Malus x domestica Borkh.) is a major global crop and the genetic diversity held within the pool of cultivated varieties is important for the development of future cultivars.The aim of this study was to investigate the diversity held within the domesticated form, through the analysis of a major international germplasm collection

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Critical left coronary main trunk stenosis, chronic occluded right coronary artery, left subclavian artery occlusion, severe aortic regurgitation and porcelain aorta in a patient with aortitis

Abstract Background Coronary involvement is rare but can be critical in patients with aortitis.Although cardiac ischemia can be resolved by coronary artery bypass grafting (CABG), patients complicated with cardiac ischemia, calcified aorta, and valve insufficiency pose difficult problems for surgeons.Case presentation A 71-year-old woman was referr

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